Schneider, Kristan

Prof. Dr. rer. nat.

Positionen

Professor, Fachgruppe Mathematik, Fakultät Angewandte Computer- und Biowissenschaften

Übersicht zur Forschung

- Statistik und Datenanalyse
- Populationsgenetik
- Biomathematik
- Malariagenetik
- COVID-19
- SARS-CoV-2
- Ebola
- Malaria
- Affenpocken
- Marburgvirus

Forschungsschwerpunkt

Angewandte Informatik Forschungsschwerpunkt

Projektleitung

Temporal Transcriptomics in Hospitalized COVID-19 Patients from Disparately Impacted Ancestral Groups for Therapeutic Discovery gefördert von University of New Mexico 2023 - 2024
Beobachtung von antimikrobieller Resistenz und Diagnoseeffizient von Malaria in Indischen Stammesgebieten zur Erreichung von Ausrottungszielen - AREMD, Teilvorhaben: methodische Neuentwicklung und statistische Auswertungen gefördert von Bundesministerium für Bildung und Forschung 2020 - 2023
Innovationsvorhaben zur Profilschärfung 2022, AP 4.12 Wissenschafts-Praxis-Transfer in der Epidemiologie von Malaria gefördert von Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus 2022
Hochschulkooperationen AIMS in Südafrika, Kamerun & Ghana 2018-2022: Mathematics against malaria within the AIMS network gefördert von Deutscher Akademischer Austauschdienst 2018 - 2022
Ökologisch nachhaltige Wertschöpfungsketten in der Landwirtschaft durch Optimierung des Insektizid-Gebrauchs aufgrund von automatisiertem Schädlings-Monitoring gefördert von Deutsche Forschungsgemeinschaft 2019 - 2022
Vorlaufforschung Technologieentwicklung 4.0, AP 8 gefördert von Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus 2019 - 2021
Innovationscluster HSMW 2021, AP 9-04: Forschungsanschub zur Steigerung der Drittmittelfähigkeit der Hochschule gefördert von Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus 2021
Innovationscluster HSMW 2021, AP 9-05: Forschungsanschub zur Steigerung der Drittmittelfähigkeit der Hochschule gefördert von Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus 2021
Vorlaufforschung Technologieentwicklung 4.0 2019 - 2021
Verbundprojekt Erschließung von mobilen Sensordaten für die Publikumsforschung durch interaktive Lernverfahren (AGILE), Teilprojekt: Empirische Netzwerkforschung gefördert von Europäische Union 2017 - 2020
Innovationsvorhaben Profilschärfung an Hochschulen für angewandte Wissenschaften, AP 6: Statistische Verfahren und Mathematische Modelle zur Analyse von genetischen Daten mit Anwendung auf Malaria gefördert von Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus 2016 - 2018
Entwicklung und Demonstration der Verwendbarkeit eines Erfassungssystems für Publikumsströme 2 (Flowbile) gefördert von Leipziger Verkehrsbetriebe GmbH 2015 - 2017
Forschungs- und Entwicklungsvorhaben zur Publikumslenkung im regionalen Personen-Nahverkehr, Teilvorhaben 1: Flowbile - Mittweidas digitaler Bewegungsmelder gefördert von Verkehrsverbund Mittelsachsen GmbH 2015 - 2017
Weiterentwicklung Flowbile-Recorder gefördert von Verkehrsverbund Mittelsachsen GmbH 2016 - 2017

ausgewählte Veröffentlichungen

Journalartikel
- Detecting Opioid Use Disorder in Health Claims Data With Positive Unlabeled Learning. IEEE Journal of Biomedical and Health Informatics. 750-757. 2025
- Microsatellites markers fostering the understanding of malaria parasite biology, epidemiology and population genetics. Diagnostic Microbiology and Infectious Disease. 2025
- A Meta Algorithm for Interpretable Ensemble Learning: The League of Experts. Machine Learning and Knowledge Extraction. 800-826. 2024
- A non-parametric approach to estimate multiplicity of infection and pathogen haplotype frequencies. Frontiers in Malaria. 2024
- Antimicrobial stewardship capacity and antibiotic utilisation practices in the Cape Coast Teaching Hospital, Ghana: A point prevalence survey study. PLOS ONE. e0297626. 2024
- Cellular immune response to SARS-CoV-2 and clinical presentation in individuals exposed to endemic malaria. Cell Reports. 114533. 2024
- Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia. Nature Communications. 5037. 2024
- Estimating multiplicity of infection, allele frequencies, and prevalences accounting for incomplete data. PLOS ONE. 2024
- Mutations in Plasmodium falciparum Kelch13 (PfK13) dysregulates PI3K/AKT signalling pathway in artemisinin resistance. Indian Journal of Medical Microbiology. 2024
- Repurposing FDA‐approved drugs to target malaria through inhibition of dihydrofolate reductase in the folate biosynthesis pathway: A prospective approach. Journal of Cellular Biochemistry. 2024
- Transcriptomic and Proteomic Insights into Host Immune Responses in Pediatric Severe Malarial Anemia: Dysregulation in HSP60-70-TLR2/4 Signaling and Altered Glutamine Metabolism. Pathogens. 867. 2024
- A flexible age-dependent, spatially-stratified predictive model for the spread of COVID-19, accounting for multiple viral variants and vaccines. PLOS ONE. e0277505. 2023
- Disproportionate impact of COVID-19 severity and mortality on hospitalized American Indian/Alaska Native patients. PNAS Nexus. 2023
- Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia. BMC Genomics. 542. 2023
- India-EMBO Lecture Course: understanding malaria from molecular epidemiology, population genetics, and evolutionary perspectives. Trends in Parasitology. 307-313. 2023
- Low Prevalence of Antimalarial Resistance Mutations in India During 2014–2015: Impact of Combining First-line Therapy With Primaquine. Journal of Infectious Diseases. 2023
- Predicting the combined effects of case isolation, safe funeral practices, and contact tracing during Ebola virus disease outbreaks. PLOS ONE. e0276351. 2023
- A maximum-likelihood method to estimate haplotype frequencies and prevalence alongside multiplicity of infection from SNP data. Frontiers in Epidemiology. 2022
- Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia. Experimental Biology and Medicine. 672-682. 2022
- Does it matter who is spreading monkeypox?. The Lancet Infectious Diseases. 2022
- Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives. Experimental Biology and Medicine. 1253-1263. 2022
- Evolutionary genetics of malaria. Frontiers in Genetics. 2022
- Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya. Tropical Medicine and Health. 41. 2022
- Investigating the impact of multiple feeding attempts on mosquito dynamics via mathematical models. Mathematical Biosciences. 108832. 2022
- Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan children. Frontiers in Genetics. 2022
- Reconsidering the incubation period of Marburg virus disease. The Lancet Infectious Diseases. 1525-1526. 2022
- Screening of potential antiplasmodial agents targeting cysteine protease-Falcipain 2: a computational pipeline. Journal of Biomolecular Structure and Dynamics. 1-44. 2022
- The many definitions of multiplicity of infection. Frontiers in Epidemiology. 2022
- Yes, it matters who is spreading monkeypox – Authors' reply. The Lancet Infectious Diseases. 1417. 2022
- An integrated virtual screening and drug repurposing strategy for the discovery of new antimalarial drugs against Plasmodium falciparum phosphatidylinositol 3‐kinase. Journal of Cellular Biochemistry. 1326-1336. 2021
- Bias-corrected maximum-likelihood estimation of multiplicity of infection and lineage frequencies. PLOS ONE. e0261889. 2021
- Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia. Frontiers in Genetics. 2021
- Is increased mortality by multiple exposures to COVID-19 an overseen factor when aiming for herd immunity?. PLOS ONE. e0253758. 2021
- Preventing COVID-19 spread in closed facilities by regular testing of employees – an efficient intervention in long-term care facilities and prisons. medRxiv. 2021
- Preventing COVID-19 spread in closed facilities by regular testing of employees—An efficient intervention in long-term care facilities and prisons?. PLOS ONE. e0249588. 2021
- The impact of COVID-19 vaccination campaigns accounting for antibody-dependent enhancement. PLOS ONE. e0245417. 2021
- Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H. Malaria Journal. 378. 2020
- Is increased mortality by multiple exposures to COVID-19 an overseen factor when aiming for herd immunity?. medRxiv. 2020
- Malaria in Venezuela: changes in the complexity of infection reflects the increment in transmission intensity. Malaria Journal. 176. 2020
- The COVID-19 pandemic preparedness simulation tool: CovidSIM. BMC Infectious Diseases. 859. 2020
- Limited differentiation among Plasmodium vivax populations from the northwest and to the south Pacific Coast of Colombia: A malaria corridor?. PLOS Neglected Tropical Diseases. e0007310. 2019
- Correction: A Likelihood Approach to Estimate the Number of Co-Infections. PLOS ONE. e0192877. 2018
- Large and finite sample properties of a maximum-likelihood estimator for multiplicity of infection. PLOS ONE. e0194148. 2018
- Profiles of low complexity regions in Apicomplexa. BMC Evolutionary Biology. 47. 2016
- Persistence of Sulfadoxine-Pyrimethamine Resistance Despite Reduction of Drug Pressure in Malawi. Journal of Infectious Diseases. 694-701. 2015
- A Likelihood Approach to Estimate the Number of Co-Infections. PLOS ONE. e97899. 2014
- A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition. PLOS ONE. e101601. 2014
- Fitness components and natural selection: why are there different patterns on the emergence of drug resistance in Plasmodium falciparum and Plasmodium vivax?. Malaria Journal. 15. 2013
- Genetic Hitchhiking under Heterogeneous Spatial Selection Pressures. PLOS ONE. e61742. 2013
- The Hitchhiking Effect of a Strongly Selected Substitution in Male Germline on Neutral Polymorphism in a Monogamy Population. PLOS ONE. e71497. 2013
- Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya. Malaria Journal. 77. 2012
- Local population structure of Plasmodium: impact on malaria control and elimination. Malaria Journal. 412. 2012
- Approximations for the hitchhiking effect caused by the evolution of antimalarial-drug resistance. Journal of Mathematical Biology. 789-832. 2011
- Evolution of Assortative Mating in a Population Expressing Dominance. PLOS ONE. e16821. 2011
- An analytical model for genetic hitchhiking in the evolution of antimalarial drug resistance. Theoretical Population Biology. 93-108. 2010
- EVOLUTION OF DOMINANCE UNDER FREQUENCY-DEPENDENT INTRASPECIFIC COMPETITION IN AN ASSORTATIVELY MATING POPULATION. Evolution. 561-582. 2010
- Maximization principles for frequency-dependent selection II: the one-locus multiallele case. Journal of Mathematical Biology. 95-132. 2010
- Generalized Hankel operators on the Fock space. Mathematische Nachrichten. 1811-1826. 2009
- Optimization under frequency-dependent selection. Theoretical Population Biology. 1-12. 2009
- Maximization principles for frequency-dependent selection I: the one-locus two-allele case. Theoretical Population Biology. 251-262. 2008
- Long-term evolution of polygenic traits under frequency-dependent intraspecific competition. Theoretical Population Biology. 342-366. 2007
- A multilocus-multiallele analysis of frequency-dependent selection induced by intraspecific competition. Journal of Mathematical Biology. 483-523. 2006
- Intraspecific Competitive Divergence and Convergence under Assortative Mating. The American Naturalist. 190-205. 2006
- THE CONDITIONS FOR SPECIATION THROUGH INTRASPECIFIC COMPETITION. Evolution. 2185-2206. 2006
- Competitive divergence in non-random mating populations. Theoretical Population Biology. 105-118. 2005
Konferenzpaper
- You can’t drive my car - a method to fingerprint individual driving styles in a sim-racing setting. 2022 International Conference on Electrical, Computer and Energy Technologies (ICECET). 2022
Konferenzposter
Meeting Abstract
- Complement component 5 (C5) missense mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia. Scientific Reports 2021, International Week 2021. 32-33. 2021
- Diversity measures. Scientific Reports 2021, International Week 2021. 32-32. 2021
- The IRESSEF – an institution conducting public health research in Senegal. Scientific Reports 2021, International Week 2021. 31-32. 2021
Preprint
Rezension
- Referee report. For: Optimal control model of human-to-human transmission of monkeypox virus [version 2; peer review: 2 approved with reservations, 1 not approved]. F1000 Research. 2023
Sammelbandbeitrag
- COVID-19 research at HSMW. Scientific Reports 2021, International Week 2021. 23-25. 2021
- Charles Darwin Meets Ronald Ross: A Population-Genetic Framework for the Evolutionary Dynamics of Malaria. Infectious Diseases and Our Planet. 149-191. 2021
- European-African Partnership Lessons Learned. Scientific Reports 2021, International Week 2021. 3-6. 2021
- Sustaining Ebola management by predictive modelling. Scientific Reports 2021, International Week 2021. 16-19. 2021
- The International Collaboration of Math Against Malaria. Scientific Reports 2021, International Week 2021. 20-22. 2021
- Measuring diversity among competing supply-value chains. Sustainability in Global Value Chains - Measures, Ethics and Best Practices for Responsible Businesses. Hrsg. Henke, Michael. 106-128. 2020

Präsentationen

Vortrag
- Fächerübergreifend, ModeratorIn, während Jahrestagung für ausländische Stipendiaten Hanns-Seidel-Stiftung 2016
- Tropenmedizin und Malariaforschung, ModeratorIn, während 65th Annual Meeting of the American Society for Tropical Medicine & Hygiene 2016
- Populationsgenetik, ModeratorIn, während Annual Retreat of Vienna Graduate School of Population genetics 2016
- A maximum-likelihood approach to estimate the number of co-infections in malaria, vortragende Person, während Big Data: mathematical methods and applied problems 2015

Mitglied bei

Vienna Graduate School of Population Genetics Assoziiertes Mitglied 2015 -

betreut/e wissenschaftliche Arbeit

Masterarbeit
- A maximum likelihood estimation of multiplicity of infection (MOI) from molecular data collected by routine screening 2015
Promotion
- Mathematische Modelle zur Prognose von Medikamentenresistenz bearbeitet durch Hashemi Eshkiki, Meraj 2016 -

andere Forschungsaktivitäten

Environmental impact on the evolution of antimalarial drug resistance

vollständiger Name

Kristan Schneider

zugehörig zur Einrichtung

6-133

Postanschrift

Am Schwanenteich 4b

Mittweida

09648

Deutschland

Postadresse

Technikumplatz 17

Mittweida

09648

Deutschland

KoautorInnen-Netzwerk

Koforscher-Netzwerk

Kontaktdaten

schneid2@hs-mittweida.de

kristan.schneider@hs-mittweida.de

+49 3727 581057